Archives of Psychiatric Nursing, vol.58, 2025 (SCI-Expanded, SSCI, Scopus)
Objective: This study aimed to determine the mediating role of psychological resilience in the relationship between illness uncertainty and psychological well-being in individuals with schizophrenia. Method: A descriptive and correlational study was conducted following the Strengthening the Reporting of Observational Studies in Epidemiology guidelines. A total of 150 participants diagnosed with schizophrenia according to the DSM-5-TR criteria were recruited for the study. Data were collected using the Personal Information Form, the Structured Clinical Interview for DSM-5, the Positive and Negative Syndrome Scale, the Mishel Uncertainty in Illness Scale–Community Form, the Psychological Well-Being Scale, and the Connor–Davidson Resilience Scale. Results: The mean age of the participants diagnosed with schizophrenia was 37.52 ± 10.62 years, and the mean age at diagnosis of schizophrenia was 30.78 ± 10.88 years. The mediating role of psychological resilience in the effect of uncertainty in illness on psychological well-being was significant (−0.1647, −0.0289). Conclusion: This study underscores the critical role of resilience in mitigating the negative effect of illness uncertainty and emphasizes the need for health professionals to assess the level of uncertainty experienced by individuals with schizophrenia, its effects on psychological well-being, and their coping mechanisms.