Çiğ Sebzelerde ESBL Üreten Escherichia coli'nin Varlığı ve Antibiyotik Direnç Profilleri

Süleymanoğlu A. A., Aydın A.

XXI. International Scientific Conference "Tradition and Modernity in Veterinary Medicine", Pazardzhik, Bulgaristan, 24 - 26 Nisan 2026, ss.50, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Pazardzhik
  • Basıldığı Ülke: Bulgaristan
  • Sayfa Sayıları: ss.50
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Antibiotic-resistant bacteria pose a major global health threat, with increasing resistance risking public health. Escherichia coli, which can be transmitted through food, is a key bacterial species involved. In this study, E. coli was found in 24.5% of raw vegetables and ready-to-eat salad samples collected in Istanbul, a large metropolitan area, in 2021, confirmed by both traditional microbiology and PCR methods. Antibiotic resistance was assessed using the disk diffusion test, showing resistance rates of 46% to tetracycline, 15% to trimethoprim–sulfamethoxazole, 15% to amoxicillin/clavulanic acid, 15% to ampicillin, and 7.6% to chloramphenicol. Multiplex PCR (mPCR) detected resistance genes at rates of 92% for blaTEM, 53.8% for blaCTX-M, and 7.6% for blaOXA. Additionally, PCR was used to screen for heavy-metal resistance genes associated with antibiotic resistance (cadD, cadX, copA, and czrC); none were detected. The detection of ESBL-related resistance genes in raw vegetables and salads highlights the need for strict food hygiene and a One Health approach. Foodborne ESBL-producing E. coli isolates represent a serious risk to public health.