Paradoxal reaction with midazolam (3 case reports)

Salihoǧlu Z. , Demiroluk Ş., Köse Y., Karaca S.

Anestezi Dergisi, vol.10, pp.69-71, 2002 (Refereed Journals of Other Institutions) identifier

  • Publication Type: Article / Article
  • Volume: 10
  • Publication Date: 2002
  • Title of Journal : Anestezi Dergisi
  • Page Numbers: pp.69-71


We report 3 cases of paradoxical reaction to midazolam after being used for premedication. The picture was characterized by a marked aggressiveness and agitation. In one case the reaction was treated with general anesthesia, whereas in the other two patients the clinical picture was rapidly reversed by administration of fentanyl. We describe the possible causative mechanisms of this reaction as well as their treatment.