20th International Scientific Conference "Tradition and Modernity in Veterinary Medicine, Sofija, Bulgaristan, 25 - 27 Nisan 2025, ss.19, (Özet Bildiri)
Esherichia coli (E. coli) is a significant bacterial species with both commensal and pathogenic variants. The pathogenic E. coli strains pose a serious threat to public health, causing epidemics and emerging in new strains on a regular basis. Both pathogenic and commensal types are increasingly becoming prominent due to their development of antibiotic resistance mechanisms. Notably, the transmission of resistance genes, particularly through mobilized genetic materials, is of particular concern. Currently, E. coli strains that produce extended-spectrum beta-lactamase and are resistant to carbapenems and colistin are major concerns. The rise of resistance in E. coli, particularly against last-resort antibiotics, poses a threat to public health and complicates the treatment of uropathogenic E. coli infections. The prevalence of multi-antibiotic resistance in E. coli complicates treatment and increases dependence on vital antibiotics. Identifying the sources of resistance in E. coli strains is crucial for combating this bacterium, but it presents a complex challenge. Its ubiquitous presence in various environments, along with its ability to spread globally through food, complicates efforts to track and contain it. Enterohemorrhagic E. coli, found in food animals and transmitted through contaminated food, poses a significant public health threat. Cross-contamination plays a crucial role in the transmission of foodborne illnesses, underscoring the importance of food safety in this context. Human and veterinary doctors should collaborate to combat antibiotic resistance and E. coli through preventive medicine, following the One Health concept.