Ameliorative effects of garlic oil on FNDC5 and irisin sensitivity in liver of streptozotocin-induced diabetic rats

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Eser N., Yoldas A., Turk A., Yigin A., Yalcin A., Cicek M.

JOURNAL OF PHARMACY AND PHARMACOLOGY, cilt.73, sa.6, ss.824-834, 2021 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 73 Sayı: 6
• Basım Tarihi: 2021
• Doi Numarası: 10.1093/jpp/rgab023
• Dergi Adı: JOURNAL OF PHARMACY AND PHARMACOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
• Sayfa Sayıları: ss.824-834
• Anahtar Kelimeler: garlic oil, irisin, FNDC5, diabetes, liver, rat, OXIDATIVE STRESS, GLUCOSE-METABOLISM, INSULIN-RESISTANCE, DIALLYL TRISULFIDE, MAP KINASE, EXTRACT, INFLAMMATION, ANTIOXIDANT, PGC-1-ALPHA, DISULFIDE
• İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objectives This study was aimed to investigate the effects of garlic oil (GO), an important natural constituent used in alleviating diabetes and its complications, on the expression levels of irisin and related genes.