Global Gene Expression Analysis of Reactive Stroma in Prostate Cancer

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Dakhova O., Ozen M., Creighton C. J., Li R., Ayala G., Rowley D., ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.15, sa.12, ss.3979-3989, 2009 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 15 Sayı: 12
• Basım Tarihi: 2009
• Doi Numarası: 10.1158/1078-0432.ccr-08-1899
• Dergi Adı: CLINICAL CANCER RESEARCH
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.3979-3989
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Purpose: Marked reactive stroma formation, designated as grade 3 reactive stroma, is associated with poor outcome in clinically localized prostate cancer. To understand the biological processes and signaling mechanisms underlying the formation of such reactive stroma, we carried out microarray gene expression analysis of laser-captured reactive stroma and matched normal stroma.