Turk Hijyen ve Deneysel Biyoloji Dergisi, cilt.74, sa.4, ss.261-268, 2017 (Scopus, TRDizin)
Objective: Acute gastroenteritis is the second frequent reason of morbidity and mortality after lower respiratory tract infections. One billion children below the age of five have diarrhea every year throughout the world, and nearly six million children are lost due to diarrhea. Knowing gastroenteritis factors enables physicians to make accurate and efficient diagnoses, and guides them to select the right antibiotic when the cases require antimicrobial treatment. In this study, the purpose is to examine the existence and frequency of Human Bocavirus in acute gastroenteritis in children between 0-5 years of age applying to our hospital. Methods: Stool samples taken from 101 children (42 female, 59 male) between the age of 0-5 with acute gastroenteritis were included in the study. The DNA of the Human Bocavirus (HBoV) was investigated with the PCR Method in which proper primary series were used for NP-1 gen area. Results: Seven (6,9%) of the 101 samples that were examined in the scope of the study were determined to be HBoV positive. The mean age of the patients who were HBoV positive was 1,5 (1-2,5 years of age); and 71,4% were below the age of two. In two of the 7 positive samples (28,6%) positivity for more than more virus (HBoV and Norovirus) was determined, and simultaneous infection was considered. Conclusion: Studies conducted to investigate the role of HBoV in gastrointestinal system infections are importantfor treatment and epidemiological purposes. Further studies are required for the purpose of determining the role of HBoV in acute gastroenteritis infections. We believe that the present study of ours will contribute to the epidemiological studies since it is the very first research in this field.