Rapidly Progressive Thyroid Mass: Amyloid Goiter


Ibrahimov M., Yilmaz M., Kilic E., Akil F., Rasidov R., Karaman E.

JOURNAL OF CRANIOFACIAL SURGERY, vol.23, no.6, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1097/scs.0b013e31825cef34
  • Title of Journal : JOURNAL OF CRANIOFACIAL SURGERY

Abstract

Amyloidosis is a disease of unknown etiology characterized by the accumulation of an amorphous proteinaceous material in various organs and tissues of the body. Amyloid goiter is an exceedingly rare pathologic condition due to massive amyloid infiltration of the thyroid tissue. Amyloid goiter occurs in association with both primary and secondary systemic amyloidosis, more commonly in the latter. Preoperatively, it simulates a multinodular goiter, and surgical intervention is often necessary to establish a diagnosis and to relieve compressive symptoms of a neck mass. We present the case of an 85-year-old female patient who presented with a rapidly enlarging goiter. Histologic examination confirmed amyloid goiter.