Relationship between fecal calprotectin level and disease activity in patients with hidradenitis suppurativa
DERMATOLOGIC THERAPY, cilt.33, sa.2, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 2
- Basım Tarihi: 2020
- Doi Numarası: 10.1111/dth.13232
- Dergi Adı: DERMATOLOGIC THERAPY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
- Anahtar Kelimeler: calprotectin, disease activity, hidradenitis suppurativa, SEVERITY, BIOMARKER
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Background Hidradenitis suppurativa is a chronic, inflammatory, recurrent disease with recurrent abscesses, and sinus tract formation leading to scarring. Calprotectin has immunomodulatory, antimicrobial, and antiproliferative properties and is a calcium-binding protein primarily found in the neutrophil cytoplasm. In recent years, a significant relationship between the activity of various diseases and the level of calprotectin has led to the conclusion that there may be a similar relationship in hidradenitis suppurativa.