Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach

KOKSAL, C.; BOZKURT, A.; USTUNDAG, N.; KONUKOGLU, DİLDAR; Musellim, Benan; SIRIN, Gökçe; CORTELEKOGLU, T.; SAYIN, A.

Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach

KOKSAL C., BOZKURT A. K., USTUNDAG N., KONUKOGLU D., Musellim B., SIRIN G., ...Daha Fazla

JOURNAL OF CARDIOVASCULAR SURGERY, cilt.47, sa.4, ss.445-449, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 47 Sayı: 4
Basım Tarihi: 2006
Dergi Adı: JOURNAL OF CARDIOVASCULAR SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.445-449
Anahtar Kelimeler: N-acetylcysteine, calcium dobesilate, aprotinin, dimethyl-sulfoxide, ischemia reperfusion injury, thiobarbituric acid reactive substances, CALCIUM DOBESILATE, N-ACETYLCYSTEINE, ISCHEMIA-REPERFUSION, APROTININ, NEUTROPHIL, INCREASES, INVITRO, DAMAGE
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Aim. The purpose of this study was to examine the effects of N-acetylcysteine (NAC), calcium dobesilate (DOBE) and aprotinin on the amelioration of lung damage following ischemia/reperfusion injury in a rat hind limb model. A well known antioxidant dimethyl-sulfoxide (DMSO) was also tested for comparison.