Circulating nuclear factor-kappa B mediates cancer-associated inflammation in human breast and colon cancer.
Journal of medical biochemistry, cilt.40, sa.2, ss.150-159, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.5937/jomb0-27128
- Dergi Adı: Journal of medical biochemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database, Directory of Open Access Journals
- Sayfa Sayıları: ss.150-159
- Anahtar Kelimeler: nuclear factor kappa-B, tumour necrosis factor-alpha, soluble TNF-related apoptosis-inducing ligand, interleukin-6, pentraxin-3, APOPTOSIS-INDUCING LIGAND, C-REACTIVE PROTEIN, PENTRAXIN 3, COLORECTAL-CANCER, TNF-ALPHA, INTERLEUKIN-6, PATHWAY, EXPRESSION, PROGNOSIS, SURVIVAL
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
Background: Inflammation is recognized as a hallmark feature of cancer development and progression. The aim of our study was to investigate the significance of serum nuclear factor kappa-B (NF-k beta) levels as a circulating marker in the monitoring of inflammation in breast and colon cancer; to show the relationship between NF-kB with inflammatory parameters as tumour necrosis factor-alpha (TNF-alpha), soluble TNF-related apoptosis-inducing ligand (sTRAIL), interleukin-6 (IL-6), pentraxin-3 (PTX-3), procalcitonin (PCT), and C-reactive protein (CRP) levels.