Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies
CURRENT ALZHEIMER RESEARCH, cilt.17, sa.3, ss.269-284, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17 Sayı: 3
- Basım Tarihi: 2020
- Doi Numarası: 10.2174/1567205017666200424133534
- Dergi Adı: CURRENT ALZHEIMER RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Abstracts in Social Gerontology, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE, Psycinfo
- Sayfa Sayıları: ss.269-284
- Anahtar Kelimeler: Alzheimer's Disease, cholinesterase inhibition, acetylcholinesterase, butyrylcholinesterase, antioxidant, docking studies, abietane diterpenoids, Salvia, ALZHEIMERS-DISEASE, ANTIBACTERIAL DITERPENES, BIOACTIVE CONSTITUENTS, CYTOTOXIC ACTIVITY, SALVIA EXTRACTS, ROOTS, TERPENOIDS, BUTYRYLCHOLINESTERASE, INHIBITORS, THERAPY
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
Background: Alzheimer's Disease (AD) is one of the most prevalent causes of dementia in the world, and no drugs available that can provide a complete cure. Cholinergic neurons of the cerebral cortex of AD patients are lost due to increased activity of cholinesterase enzymes.