The relationship between 24-hour blood pressure follow up and cognitive functions in hypertensive elderly patients


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Doventas A., Kececi Savan D., Cengiz M., Yavuzer H., Suna Erdincler D., Beger T.

EUROPEAN GERIATRIC MEDICINE, cilt.3, ss.136, 2012 (SCI-Expanded, Scopus)

Özet

The relationship between 24-hour blood pressure follow up and cognitive functions in hypertensive elderly patients A. Doventas, D. Kececi Savan, M. Cengiz, H. Yavuzer, D. Suna Erdincler∗, T. Beger Istanbul University, Cerrahpasa Medical School, Department Of Internal Medicine, Division Of Geriatrics, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey Introduction.– Objective.– To determine the relation between 24hourbloodpressurefollowupandcognitivefunctionsinhypertensive patients that are equal to or more than 60 years old and do not have any other conditions or diseases that would affect cognitive functions. Text.– Patients and method.– Ninety-nine elderly patients in Geriatry outpatient clinics between March 2011–October 2011 were accepted to the study. Patients who had diseases that may impair the cognitive functions were excluded. After GDS andSMMTapplication, 24hour ambulatory blood pressure monitorization were performed. Then the patients were subgrouped as dipper/nondipper and regulated/non-regulated. Eight patients that had GDS score equal toormorethan21weresupposedashighlydepressive and excluded from the study because of the risk of cognitive function impairment. SMMTscoreswerecomparedinthesubgroupsof dipper/non-dipper and regulated/non-regulated. Findings.– The study included 21 male and 70 female patients with a mean age of 72.5±8.1 and 71.7±7.7, respectively. No correlations were found between dipper/non-dipper and minimental groups and measures in the study subgroups (r=–0.115, P=0.277 and r=–0.049, P=0.642 respectively). As regulation of hypertension and minimental measures (regulated/non-regulated) of the study groups were reasonably significant with a direct proportion, correlation of these measures as groups were detected as highly significant with a direct proportion. Result.– There were no significant difference in SMMT measures in both dipper and non-dipper groups in pure hypertensive old patients, nondipping was notrelated to cognitive functions in pure hypertensive old patients. This study shows that new studies are needed that would be supported by subgroup analysis in selected study groups, other than existing studies in literature related to hypertension andcognitive function that had beeninterpreted differently. Disclosure.– No significant relationships. http://dx.doi.org/10.1016/j.eurger.2012.07.342