Utility of left atrial strain imaging for the determination of diastolic dysfunction in patients with STEMI

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Ohtaroğlu Tokdil N. İ. K., Öngen Z., İkitimur B., Durmaz E., Tokdil H., Koca D., ...Daha Fazla

European Society of Cardiology Congress 2021, London, Birleşik Krallık, 27 Ağustos - 01 Eylül 2021, cilt.42, sa.724, ss.38, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 42
  • Basıldığı Şehir: London
  • Basıldığı Ülke: Birleşik Krallık
  • Sayfa Sayıları: ss.38
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Introduction: Since echocardiographic parameters indicating increased left ventricular filling pressure were validated in patients with stable coro- nary artery disease and patients with acute coronary syndrome were ex- cluded, the utility of these parameters in ACS patients is not clarified. Re- cent studies suggest that left atrial strain imaging is a reliable method for the assessment of left ventricular diastolic dysfunction.

Purpose: In this study, we aimed to investigate the clinical utility of left atrial strain imaging for the detection of increased LVFP.
Methods: We prospectively included patients diagnosed with ST-segment elevation myocardial infarction who were treated with primary percuta- neous intervention (pPCI). Left ventricular end-diastolic pressure was mea- sured following the procedure. Comprehensive echocardiographic evalua- tion was performed within 24 hours of pPCI. Patients with atrial fibrillation and severe valvular heart disease were excluded. Normal LV end-diastolic pressure was accepted as <18 mmHg.

Results: 76 patients were enrolled. Patients were divided into two groups

according to LVEDP value. Group 1 patients included patients with nor- mal LVEDP (42 patients) and the rest of the patients included into group 2 (27 patients). Comorbidities including hypertension (p: 0.408), diabetes (p: 0.696) and dyslipidaemia (p: 0.336) were similar between groups. Anterior myocardial infarction was more prevalent in group 2 patients (p: 0.012). Troponin and pro-BNP values were significantly higher in group 2 patients (p: 0.001 and p: 0.03 respectively). Left ventricular ejection fraction and left ventricular global strain values were significantly lower in group 2 patients (p: 0.048 and p: 0.025 respectively). Table 1 represents the comparison of strain values between groups. Left atrial reservoir strain rates were lower in group 2 patients (p: 0.09). Correlation analyses revealed that there is a statistically significant relationship between left atrial strain values and LVEDP (p: 0.003 and r: 0.238).

Conclusion: In conclusion, our study has demonstrated that left atrial strain imaging is a useful non-invasive method for the assessment of in- creased LVEDP in patients with STEMI.