The effects of vanadyl sulfate on glutathione, lipid peroxidation and nonenzymatic glycosylation levels in various tissues in experimental diabetes
ISTANBUL JOURNAL OF PHARMACY, cilt.51, sa.1, ss.73-78, 2021 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 51 Sayı: 1
- Basım Tarihi: 2021
- Doi Numarası: 10.26650/istanbuljpharm.2020.0107
- Dergi Adı: ISTANBUL JOURNAL OF PHARMACY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Sayfa Sayıları: ss.73-78
- Anahtar Kelimeler: Diabetes mellitus, vanadyl sulfate, oxidative stress, cardiac, lens, lung, skeletal muscle, OXIDATIVE STRESS, MELLITUS, INSULIN, ACTIVATION, PRODUCTS, PROTECTS, STOMACH
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Background and Aims: Diabetes mellitus is characterized by hyperglycemia which over time leads to serious damage of several body systems. Vanadium ions and their complexes have been demonstrated to have various insulin-mimetic and antidiabetic effects. The object of the present work was to investigate the effect of vanadyl sulfate ( VS) on serum total lipid and protein parameters, glutathione, lipid peroxidation and nonenzymatic glycosylation levels in cardiac, lens, lung and skeletal muscle tissues of STZ diabetic rats.