The impact of continuous renal replacement therapy for metabolic disorders in infants


Aygun F. , Aygun D. , Alp F. E. , Zubanoglu T. , Zeybek C. , Cam H.

PEDIATRICS AND NEONATOLOGY, vol.59, no.1, pp.85-90, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1016/j.pedneo.2017.04.004
  • Title of Journal : PEDIATRICS AND NEONATOLOGY
  • Page Numbers: pp.85-90
  • Keywords: renal replacement therapy, metabolic emergency, hyperammonemia, leucine, child, SYRUP-URINE-DISEASE, CONTINUOUS ARTERIOVENOUS HEMOFILTRATION, INBORN-ERRORS, NONRENAL INDICATIONS, PERITONEAL-DIALYSIS, CHILDREN, HEMODIALYSIS, REGISTRY, FAILURE, INJURY

Abstract

Background: While Continuous Renal Replacement Therapy (CRRT) is a well established treatment modality for patients with acute kidney insufficiency (AKI), it is now also being used for the management of various illnesses such as acute metabolic disorders presenting with hyper-ammonemia and elevated leucine levels. Herein, we aimed to describe our experience with CRRT in treatment of acute decompensation of 14 patients with a diagnosis of metabolic disorder who has been admitted to our pediatric intensive care unit (PICU) in the last year.