Role of H-FABP values in determining the etiologic factors of the cardiac injuries


Akpinar G., Duman A., Gulen B., Kapci M., Altinbilek E., İKİZCELİ İ.

The Pan African medical journal, cilt.26, ss.36, 2017 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26
  • Basım Tarihi: 2017
  • Doi Numarası: 10.11604/pamj.2017.26.36.8746
  • Dergi Adı: The Pan African medical journal
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.36
  • Anahtar Kelimeler: cardiac injury, H-FABP, thoracic trauma
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 patients with blunt thoracic injury who were admitted to our emergency service within a period of 8 months and 50 cases as controls were included in our study. RESULTS: Of the 50 patients with blunt thoracic injury in our study, 88% were male while 12% were female. The average age of the patients was 43 ± 15.15. While 27 (54%) of the 50 patients with blunt thoracic injury had cardiac injury, 23 (46%) did not have cardiac injury. The results of the statistical analyses showed a significant association between thorax trauma and cTnI, CPK, CPKMB and H-FABP (p<0.05). While there was a significant association between cardiac injury resulting from thoracic trauma and cTnI, ECG and TTE (p<0.05), there was no significant association between CPK, CPKMB and H-FABP (p>0.05). CONCLUSION: In thoracic traumas, cardiac injury diagnosis can be made as a result of the assessment with Troponin-I, ECG and ECHO. For cardiac injury diagnosis, wide scale prospective studies are needed for H-FABP use.