HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, vol.37, no.9, pp.1344-1348, 2015 (Journal Indexed in SCI)
Article / Article
Title of Journal :
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
laryngeal squamous cell carcinoma, B-crystallin, metastasis, quantitative real-time polymerase chain reaction (qRT-PCR), lymph node, HEAT-SHOCK PROTEINS, POOR-PROGNOSIS, SURGERY, MARKER, ANGIOGENESIS, CHEMOTHERAPY, ONCOPROTEIN, METASTASIS, ACTIVATION, RADIATION
BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. The recent studies suggested that B-crystallin might play an important role in tumorigenesis. The purpose of this study was to investigate the B-crystallin expression level in metastatic and nonmetastatic laryngeal SCC tissues and to determine its prognostic significance.