Chromosomal and microsatellite instability in sporadic gastric cancer

Hiyama T., Tanaka S., Yoshihara M., Sasao S., Kose K., Shima H., ...Daha Fazla

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, cilt.19, sa.7, ss.756-760, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 7
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1111/j.1440-1746.2004.03369.x
  • Dergi Adı: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.756-760
  • Anahtar Kelimeler: chromosomal instability, gastric cancer, genomic instability, microsatellite instability, REPLICATION ERROR PHENOTYPE, GENE, P53, HETEROZYGOSITY, EXPRESSION, MUTATIONS, STOMACH, MARKER
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Background: Gastric cancer can progress through two pathways of genomic instability: chromosomal (CIN) and microsatellite instability (MSI). It is hypothesized that these two pathways are not always independent and that some tumors show overlap between these two mechanisms.