Chromosomal and microsatellite instability in sporadic gastric cancer

Hiyama T., Tanaka S., Yoshihara M., Sasao S., Kose K., Shima H., ...More

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol.19, no.7, pp.756-760, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 7
  • Publication Date: 2004
  • Doi Number: 10.1111/j.1440-1746.2004.03369.x
  • Title of Journal : JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Page Numbers: pp.756-760

Abstract

Background: Gastric cancer can progress through two pathways of genomic instability: chromosomal (CIN) and microsatellite instability (MSI). It is hypothesized that these two pathways are not always independent and that some tumors show overlap between these two mechanisms.