Treatment with daptomycin of an unusual case of left-sided infective endocarditis due to Corynebacterium jeikeium
Kuwait Medical Journal, cilt.58, sa.2, ss.144-147, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 58 Sayı: 2
- Basım Tarihi: 2026
- Dergi Adı: Kuwait Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.144-147
- Anahtar Kelimeler: Corynebacterium jeikeium, daptomycin, infective endocarditis, vancomycin
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Corynebacterium jeikeium is a gram positive, aerobic rod that constitutes a major component of the bacterial flora of the human skin and mucosal membrane. Skin flora is an important source of microorganisms that cause infective endocarditis. Vancomycin is commonly used in the treatment of gram positive infections. Daptomycin is used in the treatment of infections caused by resistant gram positive microorganisms. It is a lipopeptide new drug and has been successfully used in the treatment of complicated skin infections and right-sided infective endocarditis. We report an unusual case of left-sided infective endocarditis due to Corynebacterium jeikeium which was initially unresponsive to vancomycin therapy, and then successfully treated with high-dose (12mg/kg/day) daptomycin. She was still doing well clinically.