Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease

DEMIRKAYA, Erkan; Zhou, Qing; Smith, Carolyne; Ombrello, Michael; Deuitch, Natalie; Tsai, Wanxia; Hoffmann, Patrycja; Remmers, Elaine; TAKEUCHI, Masaki; Park, Yong; CHAE, JaeJin; Barut, KENAN; SIMSEK, Dogan; Adrovic, Amra; Sahin, SEZGİN; Caliskan, SALİM; CHANDRASEKHARAPPA, Settara; HASNI, Sarfaraz; OMBRELLO, Amanda; GADINA, Massimo; KASTNER, Daniel; KAPLAN, Mariana; Kasapcopur, ÖZGÜR; AKSENTIJEVICH, Ivona

doi:10.1002/art.40158

Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease

DEMIRKAYA E., Zhou Q., Smith C. K., Ombrello M. J., Deuitch N., Tsai W. L., ...Daha Fazla

ARTHRITIS & RHEUMATOLOGY, cilt.69, sa.9, ss.1832-1839, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 69 Sayı: 9
Basım Tarihi: 2017
Doi Numarası: 10.1002/art.40158
Dergi Adı: ARTHRITIS & RHEUMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1832-1839
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Objective. To identify a genetic cause of early-onset systemic lupus erythematosus (SLE) in a large consanguineous family from Turkey and to study the mechanisms of the disease.