Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model

Gurses I., Ozeren M., Serin M., YÜCEL N., Erkal H. S.

PATHOLOGY RESEARCH AND PRACTICE, vol.210, no.12, pp.863-871, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 210 Issue: 12
  • Publication Date: 2014
  • Doi Number: 10.1016/j.prp.2014.08.006
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.863-871
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Introduction: Melatonin is a hormone which is known to be a powerful cardioprotective agent due to its free radical-scavenging properties. This study was carried out to evaluate whether melatonin administration prior to irradiation would have a protective effect on cardiac histopathological changes in an experimental rat model.