Pharmacotherapy for older people with obesity

Boyle L. D., Akbas F., Yazıcı D., McGowan B. M., YUMUK V. D.

European Journal of Internal Medicine, cilt.130, ss.33-37, 2024 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 130
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1016/j.ejim.2024.05.006
  • Dergi Adı: European Journal of Internal Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.33-37
  • Anahtar Kelimeler: Elderly, Obesity, Older people, Pharmacotherapy, Sarcopenia
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Rates of obesity continue to rise, including in older adults. Use of medication for obesity in the elderly has been considered controversial, due to concerns around potential progression of age-related sarcopenia and a general lack of evidence for its use in this age group. Within this review, we describe the general considerations when prescribing obesity pharmacotherapy for older adults living with obesity. We evaluate in detail the anti-obesity medications currently licenced in Europe, with emphasis on the available efficacy, safety and cardiovascular outcome data gathered from study of older people. Finally, we discuss future directions and avenues of research.