Preoperative Somatostatin Analogue Treatment Might Trigger Apoptosis and Autophagy in Tumor Tissues of Patients with Acromegaly: A Pilot Study.

Dagistanli, FATMA; Ozkaya, HANDE; Kucukyoruk, B.; Biceroglu, H.; Metin, D.; Gazioglu, Makbule; Oz, AYŞİM; Kadioglu, PINAR; Ozturk, MELEK

doi:10.1055/s-0042-107243

Preoperative Somatostatin Analogue Treatment Might Trigger Apoptosis and Autophagy in Tumor Tissues of Patients with Acromegaly: A Pilot Study.

Dagistanli F., Ozkaya H. M., Kucukyoruk B., Biceroglu H., Metin D., Gazioglu N., ...Daha Fazla

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, cilt.126, sa.3, ss.168-175, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 126 Sayı: 3
Basım Tarihi: 2018
Doi Numarası: 10.1055/s-0042-107243
Dergi Adı: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.168-175
Anahtar Kelimeler: acromegaly, apoptosis, autophagy, somatostatin, MEDIATED CLEAVAGE, BCL-2 FAMILY, BECLIN 1, OCTREOTIDE, CELLS, SURVIVIN, EXPRESSION, RESISTANCE, THERAPY, PROTEIN
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Objective To evaluate the effect of preoperative somatostatin analog (SRL) treatment on proteins associated with apoptosis and autophagy in patients with acromegaly and to determine factors correlating with these parameters.