Evaluation of the Effect of Antioxidant Pretreatment Timing on Ischemia-Reperfusion Injury in the Rat Inferior Epigastric Island Flap Model

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Sirkeci C. B., Yalçın C. E., Aydın S. Y., Sağır M. S., Yılmaz Ç., Mertol Ş., ...Daha Fazla

XIII. Congress of the World Society for Reconstructive Microsurgery, Barcelona, Barcelona, İspanya, 23 - 26 Nisan 2025, ss.10, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Barcelona
  • Basıldığı Ülke: İspanya
  • Sayfa Sayıları: ss.10
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Aim: Free flap surgeries represent significant advancements in reconstructive surgery. Despite surgical progress, ischemia-reperfusion injury (IRI) due to vascular complications remains a challenge, potentially leading to flap loss. Various strategies, including surgical methods and pharmacological treatments, have been explored to mitigate IRI. Among these, antioxidant treatments have garnered interest, but research on the optimal timing of antioxidant administration is lacking. This study addresses this gap by investigating the timing of antioxidant pretreatment.