Akademik Veri Yönetim Sistemi
Uluslararası Katılımlı 31. Türk Kardiyoloji Kongresi, Antalya, Türkiye, 22 - 25 Ekim 2015, ss.31, (Özet Bildiri)
Introduction: The Clinical SYNTAX Score (CSS) combines anatomical and clinical risk assessment. This
study was designed to evaluate CSS as a predictor of prognosis in patients with ST-elevation myocardial
infarction (STEMI) undergoing primary percutaneous coronary intervention (p-PCI).
Materials and Method: We evaluated 433 patients who were diagnosed with STEMI and underwent p-PCI.
CSS was calculated by multiplying the anatomically derived SYNTAX score (Sx) by the modified ACEF (age,
creatinine, ejection fraction) score. Patients were divided into tertiles according to the CSS: CSSLOW ≤14
(n=141), 14< CSSMID ≤26 (n=144) and CSSHIGH >26 (n=148). The primary endpoints were defined as allcause
mortality, myocardial infarction (MI), and cerebrovascular events (CVE) over 15 months’ follow-up.
Results: Primary endpoints occurred in 9.2% of patients with CSS ≤14, 12.5% of those with 14 <CSS ≤26, and
28.4% of those with CSS >26 (p<0.001). Kaplan–Meier analysis showed that the CSS >26 group had a significantly
higher incidence of primary endpoints (p [log-rank] <0.001). CSS >26 was identified as an independent
predictor for all-cause mortality, MI, and CVE (odds ratio [OR] 4.58, 95% confidence interval [CI] 1.65–12.73,
p=0.004). Receiver operating characteristic analysis found areas under the curve of 0.66, 0.59, and 0.64 for
CSS, Sx, and ACEF (p<0.001, 0.01, <0.001, respectively).
Discussion and Conclusion: CSS may be better than Sx score or ACEF for predicting long-term prognosis in
patients with STEMI undergoing primary PCI.