The Effects of Colchicum baytopiorum on Regulatory Genes of Apoptotic and Autophagic Cell Death in HeLa Cells.

Ozsoylemez O. D., Ozturk M., Sutlupinar N., Kayacan S., Tuncdemir M., Ozcan G.

Current pharmaceutical biotechnology, cilt.17, sa.15, ss.1369-1376, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 15
  • Basım Tarihi: 2016
  • Doi Numarası: 10.2174/1389201018666161109113543
  • Dergi Adı: Current pharmaceutical biotechnology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1369-1376
  • Anahtar Kelimeler: Apoptosis, autophagy, cancer theraphy, cell death, Colchicum baytopiorum, HeLa cells, CANCER DEVELOPMENT, MEDIATED CLEAVAGE, CROSSTALK, BECLIN-1, TARGET, PUMA, STIMULATION, INTERPLAY, RELEASE, EXTRACT
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Background: The natural products have increasing important for the development of anticancer agents. Colchicum baytopiorum C.D. Brickell (C. baytopiorum), an endemic species for Turkey, contains colchicine and its derivatives. Stimulation of apoptotic and autophagy-mediated cell deaths are effective strategy for anticancer therapies.