Genetic alterations in human prostate cancer: A review of current literature
ANTICANCER RESEARCH, cilt.20, ss.1905-1912, 2000 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 20
- Basım Tarihi: 2000
- Dergi Adı: ANTICANCER RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1905-1912
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
We review the literature dealing with genetic alterations in human prostate cancer. We also discuss genetic predisposition and the roles of various proto-oncogenes and tumor-suppressor genes in prostate cancer initiation, progression, and metastasis. The role of telomere dynamics in prostate cancer metastasis and the induction of apoptosis is also briefly discussed.