Akademik Veri Yönetim Sistemi
167th Annual Meeting of the American Psychiatric Association , New York, Amerika Birleşik Devletleri, 3 - 07 Mayıs 2014, ss.462, (Özet Bildiri)
Background: :ECT has been shown to be an effective treatment for patients with schizophrenia presented with catatonia,
depression, mania and other prominent affective features. ECT
is currently underused in many psychiatric settings due to the
stigmatized perception of patients, their families and mental
health professionals.
Aim: The aims of the study were to describe the indications for
ECT among patients admitted with acute psychotic episode to
a tertiary psychiatric department in Turkey. We also aimed at
assessing whether patients with schizophrenia who received
ECT differed in their clinical history, diagnosis, severity of illness, psychopathology, and duration of hospital stay, compared
to patients who did not receive it.
Methods: This was a naturalistic prospective study of 32
patients admitted with acute exacerbation of psychosis, 8 (25
%) of which received ECT. The sociodemographic details, past
psychiatric history, comorbid personality, and substance use
details were recorded by a semi-structured interview method.
Clinical diagnosis was confirmed by two consultant psychiatrists based on DSM-IV-TR (Diagnostic and Statistical Manual of
Mental Disorders). Psychopathology was assessed within 3 days
of admission and just prior to discharge using the Positive and
Negative Syndrome Scale (PANSS). Total duration of the stay in
the hospital was also recorded.
Results: In patients who received ECT (n=8) the major indication was to augment pharmacotherapy. Drug choice was similar
between groups. Duration of hospitalization was longer in the
ECT group compared to teh group of patients which didn’t
receive ECT (mean: 34 days vs 26, p=0.04). Severity of negative
symptoms in admission was significantly higher in patients who
received ECT (33.7 vs 27, p=0.025, u:83). The decrease in negative symptoms between admission and discharge was higher
in ECT group, although the difference didn’t reach statistical
significance (mean:17 in ECT group versus 11.3 in non-ECT
group, p=0.1).
Conclusion: This preliminary study indicates a preference
among treating physicians for ECT in the presence of more severe negative symptoms in schizophrenia. Also, further studies
aiming to test whether ECT could be effective in ameliorating
the negative symptoms in schizophrenia might be warranted