F-wave and motor-evoked potentials during motor imagery and observation in apraxia of Parkinson disease.


Gunduz A. , Kiziltan M. E.

Muscle & nerve, vol.52, no.6, pp.1072-7, 2015 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1002/mus.24663
  • Title of Journal : Muscle & nerve
  • Page Numbers: pp.1072-7

Abstract

Introduction: The amplitudes of F-waves and motor-evoked potentials (MEPs) increase during imagination or active motor performance. The aim of this study was to investigate F-wave and MEP facilitation during assessment of apraxia. Methods: Eight Parkinson disease (PD) patients with apraxia, 11 patients without apraxia, and 8 healthy volunteers were enrolled. F-waves and MEPs were recorded during 4 states (resting, imagination, observation, and active movement). Results: The mean amplitude of the F-waves increased significantly during imagination and active movement as compared with at rest in healthy individuals (P = 0.028) and in the nonapraxia group (P = 0.005). PD patients with apraxia did not have similar facilitation. The mean amplitude of the MEPs also showed a similar loss of facilitation in PD with apraxia. Conclusions: Loss of facilitation during the preparation for movement is closely related to the "gold standard" clinical praxis battery. This study provides additional support and a potential electrophysiological assessment method for apraxia in PD.