Akademik Veri Yönetim Sistemi
2nd. International Food Chemistry Congress, Antalya, Türkiye, 16 - 19 Mart 2023, cilt.3, ss.36, (Özet Bildiri)
Sports supplements (SS) frequently contain adulterants, which is a serious issue in the world. SS has brought the risks of quality control, security, deliberate mislabeling and contamination1 . Depending on the use of these, clinical poisoning, organ or system damages have begun to become widespread. Also, it is reported that illegal or drug-related compounds are viewed as adulterations. Amphetamine, ephedrine, sibutramine and 1,3- dimethylamiylamine (DMAA) are just a few of known adulterants that have been identified in SS researches2 . Users describe these items, which feature mystical formulations in their advertising, as having a performance-boosting effect1 . So, this situation may cause users to engage in crimes unconsciously. Cinnarizine, which is frequently taken to treat travel sickness, is one of the second-leading causes of Parkinson's and has serious side effects3 . Cinnarizine can easily be converted into piperazine components, which currently replaces ecstasy as a “Street drug” 4 . This circumstance demonstrates the potential hazard of SS used for health and highlights their significance in forensic investigations. The analytical and legal aspects of cinnarizine determination in various SS in Turkish markets are reported in this study. Detection and confirmation of cinnarizine and its by-products were achieved by the m/z ratio and the mass spectral fragmentation pattern. To the best of our knowledge, "Cinnarizine" active compound was detected in SS for the first time ever. Due to its rapid degradation, it is crucial to isolate and identify cinnarizine and its by-products, especially 1-benzylhydrylpiperazine 5 . In this respect, it is of great importance for public health to be able to market SS, which has a multi-billion-dollar market and is dominated by numerous advertisements, in a reliable manner with precision inspections conducted by the competent authorities and highquality control. Also, new analyzing methods which especially focused on easily degradable compounds might resolve those uncertainties in this area