Ultrasound in Medicine and Biology, cilt.26, 2000 (SCI-Expanded, Scopus)
US-guided fine needle aspiration (FNAB) followed by core biopsy (CB) were performed in 67 nonpalpable breast lesions in order to compare the advantages and disadvantages. A cytopathologist was present on site to evaluate the adequacy of the aspirated material in all procedures. Operation was performed in 47 lesions including all lesions with atypical or malignant results in either biopsy method as well as those with suspicious radiological findings. The others were followed up for a minimum of 2 years. Nineteen lesions were malignant and 48 were benign. Accuracy was 82.09% in FNAB and 95.52% in CB. CB revealed the correct diagnosis in 11 out of 12 lesions in which FNAB results were either insufficient or incorrect. In 2 lesions with a true positive FNAB result, CB was false negative. Complication rate was 0% for FNAB and 5.97% for CB. FNAB is more practical, less expensive, and less invasive than CB in the diagnosis of breast lesions but yields more insufficient or false negative results. We think that FNAB should be combined with CB in those cases that the aspirated material is insufficient or the biopsy result does not agree with radiological findings.