Increased Transforming Growth Factor- Levels Associated With Cardiac Adverse Events in Hypertrophic Cardiomyopathy

Ayca, Burak; Sahin, Irfan; Kucuk, Suat; Akin, Fatih; Kafadar, Didem; Avsar, Murat; Avci, Ilker; Gungor, Baris; Okuyan, Ertugrul; Dinckal, Mustafa

doi:10.1002/clc.22404

Increased Transforming Growth Factor- Levels Associated With Cardiac Adverse Events in Hypertrophic Cardiomyopathy

Ayca B., Sahin I., Kucuk S. H., Akin F., Kafadar D., Avsar M., ...More

CLINICAL CARDIOLOGY, vol.38, no.6, pp.371-377, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 38 Issue: 6
Publication Date: 2015
Doi Number: 10.1002/clc.22404
Journal Name: CLINICAL CARDIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.371-377
Open Archive Collection: AVESIS Open Access Collection
Istanbul University-Cerrahpasa Affiliated: No

Abstract

BackgroundHypertrophic cardiomyopathy (HCM) is a common genetic heart disease characterized by ventricular hypertrophy, myocardial fibrosis, and impaired ventricular relaxation. The exact mechanisms by which fibrosis is caused remain unknown.