Serum gamma-glutamyltranspeptidase distinguishes non-alcoholic fatty liver disease at high risk

Tahan V., Canbakan B., Balci H., DANE F., Akin H., Can G., ...Daha Fazla

HEPATO-GASTROENTEROLOGY, cilt.55, sa.85, ss.1433-1438, 2008 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 85
  • Basım Tarihi: 2008
  • Dergi Adı: HEPATO-GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1433-1438
  • Anahtar Kelimeler: non-alcoholic fatty liver disease, gamma-glutamyltranspeptidase, hepatocyte apoptosis, fibrosis, HEPATITIS-C VIRUS, NF-KAPPA-B, BIOCHEMICAL MARKERS, ALCOHOLIC STEATOHEPATITIS, HEPATOCYTE APOPTOSIS, INJURY, ACTIVATION, EXPRESSION, FIBROSIS, RAT
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Background/Aims: Hepatocyte apoptosis is an important and invasive predictor of liver injury and fibrosis in non-alcoholic fatty liver disease (NAFLD). Increased gamma-glutamyltranspeptidase (GGT) level is frequently observed in NAFLD. Hepatocyte growth factor (HGF) Stimulates fibrogenesis and is correlated with GGT. The study aimed to determine whether GGT can distinguish NAFLD) patients at high risk.