Trifluoromethylthiolation of Unsymmetrical lambda(3)-Iodane Derivatives: Additive-Free, Selective and Scalable Introduction of the SCF3 Group
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no.6, pp.1091-1094, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: Issue: 6
- Publication Date: 2016
- Doi Number: 10.1002/ejoc.201501623
- Journal Name: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1091-1094
- Istanbul University-Cerrahpasa Affiliated: No
Abstract
The reaction of copper trifluoromethyl sulfide with diaryliodonium salts provides a straightforward pathway for the synthesis of aryl trifluoromethyl thioethers under mild reaction conditions and within short reaction times. High chemoselectivity was achieved by using mesityl as a leaving group. A large range of novel [(het)aryl](mesityl)iodonium salts underwent this reaction under the optimized conditions to give the desired products in moderate to good yields.