Fatigue in chronic inflammatory demyelinating polyradiculoneuropathy
10th Congress of the European Academy of Neurology, Helsinki, Finlandiya, 29 Haziran - 02 Temmuz 2024, ss.409, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Basıldığı Şehir: Helsinki
- Basıldığı Ülke: Finlandiya
- Sayfa Sayıları: ss.409
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Fatigue in chronic inflammatory demyelinating polyradiculoneuropathy
Background and Aims: Fatigue is a common symptom in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), significantly affecting the patients’ quality of life. In this study, we aimed to evaluate the severity of fatigue in CIDP patients and its correlation to other clinical and electrophysiological parameters. Methods: This is a prospective study. We invited all patients with CIDP diagnosis according to latest criteria and performed Fatigue Severity Scale (FSS), INCAT (Inflammatory Neuropathy Cause and Treatment Disability Scale), I-RODS (Inflammatory Rasch-built Overall Disability Scale), Hamilton Depression Rating Scale (HAM-D), Pittsburgh Sleep Quality Index (PSQI) and Visual Analogue Scale (VAS) for pain, nerve conduction studies. The final score on FSS represents the average of nine items; a score above 4.0 indicates the presence of fatigue. We compared the clinical and electrophysiological findings between patients with and without fatigue. Results: There were 27 patients with CIDP in study period (mean age: 54 ± 12.6 years; age range 19 and 73 years; %29.6 women). Among patients included, 26% had fatigue. All patients with fatigue had axonal involvement in the follow-up examination. The number of nerves with conduction block or reduced conduction velocity did not differ between groups. INCAT and I-RODS scales did not differ significantly between groups while PSQI, HAM-D and VAS scores were slightly higher in the fatigue group. Conclusion: Fatigue can be related to various factors independent of disease progression; such as sleep, depression and pain. Disclosure: Funding: TUSEB 2023-B-01 Group B Project.