JOURNAL OF NEUROSURGERY-SPINE, vol.2, no.3, pp.327-334, 2005 (Journal Indexed in SCI)
Article / Article
JOURNAL OF NEUROSURGERY-SPINE
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Istanbul University-Cerrahpasa Affiliated:
Object. Apoptosis is considered one of the most significant mechanisms in the pathogenesis of neuronal damage after spinal cord injury (SCI). This form of cell death occurs via mediators known as caspases. The aim of this study was to evaluate the neuroprotective effect of the caspase-9 inhibitor, z-LEHD-fmk, in a rat model of spinal cord trauma.