Association of headaches and the metals

Donma O. , Donma M.

BIOLOGICAL TRACE ELEMENT RESEARCH, vol.90, pp.1-14, 2002 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 90
  • Publication Date: 2002
  • Doi Number: 10.1385/bter:90:1-3:1
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1-14
  • Istanbul University-Cerrahpasa Affiliated: No


Lack of specific markers constitutes a problem during diagnosis of headache syndromes. Recently, some metals have gained importance as biological parameters for the diagnosis and during treatment. Low-ionized Mg and high-ionized Ca/Mg in patients with daily migrainous headaches were noted. The blood Na level was shown to increase before and during headache. Headache is also a symptom of the common cold for which zinc may be an effective therapy. The existing relationship between genetic markers of the cluster headache and the efficacy of lithium salts therapy was noted.