Bacteroidetes and Firmicutes levels in gut microbiota and effects of hosts TLR2/TLR4 gene expression levels in adult type 1 diabetes patients in Istanbul, Turkey


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Demirci M., Bahar T., Taner Z., Keskin F., Çağatay P., Ozturk B., ...More

JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.34, no.2, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1016/j.jdiacomp.2019.107449
  • Journal Name: JOURNAL OF DIABETES AND ITS COMPLICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Keywords: Type 1 diabetes, Bacteroidetes, Firmicutes, Gut microbiota, Toll-like receptors, INTESTINAL MICROBIOTA, QUANTITATIVE PCR, FECAL MICROBIOTA, CHILDREN, BLOOD, TLR4
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Aim: The aim of this study was to determine and compare the levels of both Bacteroidetes and Firmicutes in the gut microbiota and TLR2/TLR4 gene expression in the blood of patients with type 1 diabetes mellitus (T1DM) and healthy individuals. These results may serve as a preliminary assessment to guide future research.